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Kinetic examination of ligand exchange reaction between99mTc-gluconate and dimercaptosuccinic acid
Authors:J Imre
Institution:(1) Institute of Isotopes of the Hungarian Academy of Sciences, P. O. Box 77, H-1525 Budapest, Hungary
Abstract:99mTc-dimercaptosuccinic acid is one of the most widely applied radiopharmaceutical for renal scintigraphy. This complex was prepared by ligand exchange reaction from99mTc-gluconate at tracer concentration of technetium under acidic conditions. The exchange yield was determined by paper chromatography and reaction rate constants were calculated at different pH values.
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