Synthesis of 3-aryl-4-oxothiazolin-2-yl(4-ethoxy-3-methoxy)phenyl hydrazones as possible anticonvulsants

Several 3-aryl-4-oxo-thiazolin-2-yl(4-ethoxy-3-methoxy)phenyl hydrazones were synthesized and evaluated for their anticonvulsant activity. Three of these substituted hydrazones provided 80% protection against pentylenetetrazol-induced convulsions in mice.