|
|||||
|
|
Nanoscale assembly of amine-functionalized colloidal iron oxide |
|
| Authors: | KC Barick Pottumarthi V Prasad Dhirendra Bahadur |
| Institution: | a Department of Metallurgical Engineering and Materials Science, Indian Institute of Technology Bombay, Mumbai 400076, India b Department of Physics, Indian Institute of Technology Bombay, Mumbai 400076, India c Department of Radiology, Evanston Northwestern Healthcare, Evanston, IL 60201, USA d Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA e International Institute for Nanotechnology, Northwestern University, Evanston, IL 60208, USA f Centre for Research in Nanotechnology and Science, Indian Institute of Technology Bombay, Mumbai 400076, India |
| Abstract: | We demonstrate a single-step facile approach for highly water-stable assembly of amine-functionalized Fe3O4 nanoparticles using thermal decomposition of Fe-chloride precursors in ethylene glycol medium in the presence of ethylenediamine. The average size of nanoassemblies is 40±1 nm, wherein the individual nanoparticles are about 6 nm. Amine-functionalized properties are evident from Fourier transform infrared spectrometer (FTIR), thermal and elemental analyses. The saturation magnetization and spin-echo r2 of the nanoassemblies were measured to be 64.3 emu/g and 314.6 mM−1 s−1, respectively. The higher value of relaxivity ratio (r2/r1=143) indicates that nanoassemblies are a promising high-efficiency T2 contrast agent platform. |
| Keywords: | Nanoparticle Nanoassembly MR contrast agent Surface functionalization Iron oxide |
| 本文献已被 ScienceDirect 等数据库收录！ | |