| Abstract: | Macrocycles possess potential applications in supramolecular chemistry and biosystems.Thus development of new kinds of macrocycles is of significance.Herein,novel macrocycles containing Se-Se/Se-S bonds were synthesized via transformation between selenium related dynamic covalent bonds.A monomer containing two ebselen moieties was synthesized(M1).The Se-N bonds in M1 were reduced by dithiothreitol,forming Se-S linked dimer(D1).To realize the transformation from Se-S bonds to Se-Se bonds,guest molecules were added as template,triggering the formation of Se-Se linked dimer(D2).The formation of these two new kinds of macrocycles was determined by ~1H NMR and ~(77)Se NMR,and the necessity of guest molecules was also confirmed.The introduction of ebselen moieties and Se-S bonds or Se-Se bonds into macrocycles may endow it with new responsiveness and bioactivities,as well as new types of host-guest chemistry. |
