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Illuminating Molecular Processes in Living Cells
Authors:Yoshio Umezawa
Abstract:Lately, scientists have explored approaches to developing fluorescent and/or bioluminescent indicators to pinpoint cellular processes in single living cells. These analytical methods have become a key technology for visualizing and detecting what was otherwise unseen in live cells. The target signaling included second messengers, protein phosphorylations, protein–protein interactions, and protein localizations.
Keywords:cellular signaling  FRET (fluorescence resonant energy transfer)  imaging agents  optical probes  phosphorylation
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