Assembly of DNA Nanostructures with Branched Tris‐DNA |
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Authors: | Takahiro Kuroda Yoshimasa Sakurai Yukinao Suzuki AkikoO Nakamura Masayasu Kuwahara Hiroaki Ozaki Hiroaki Sawai |
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Institution: | Takahiro Kuroda,Yoshimasa Sakurai,Yukinao Suzuki,Akiko?O. Nakamura,Masayasu Kuwahara,Hiroaki Ozaki,Hiroaki Sawai |
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Abstract: | Branched tris‐DNA, in which two oligonucleotides of the same sequence and one other oligonucleotide of a different sequence are connected with a rigid central linker, was prepared chemically by using a DNA synthesizer. Two branched tris‐DNA molecules with complementary DNA sequences form dimer and tetramer as well as linear and spherical oligomer complexes. The complex formation was studied by UV/thermal denaturation, enzyme digestion, gel electrophoresis, and AFM imaging. |
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Keywords: | branched tris‐DNA DNA assembly nanostructures oligomerization oligonucleotides |
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