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Synthesis of new ferrocene derivatives with a 4,5-dichloroisothiazole fragment
Authors:A.?V.?Kletskov  author-information"  >  author-information__contact u-icon-before"  >  mailto:avkletskov@gmail.com"   title="  avkletskov@gmail.com"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author,I.?A.?Kolesnik,E.?A.?Dikusar,N.?A.?Zhukovskaya,V.?I.?Potkin
Affiliation:1.Institute of Physical Organic Chemistry,National Academy of Sciences of Belarus,Minsk,Belarus
Abstract:Conjugates of ferrocene and 4,5-dichloroisothiazole were synthesized, where the ferrocene and isothiazole moieties are linked through various structural fragments. The acylation of ferrocene with 4,5- dichloroisothiazole-3-carbonyl chloride gave (4,5-dichloroisothiazol-3-yl) ferrocenyl ketone; the acylation of aminomethylferrocene furnished the corresponding amide. The esterification of ferrocene-1,1′-dicarboxylic acid with 4,5-dichloroisothiazol-3-yl-methanol resulted in the formation of the corresponding ester. The condensation of 1,1′-diacetylferrocene with 4,5-dichloroisothiazole-3-carbaldehyde afforded ferrocenophane containing 4,5-dichloroisothiazole moieties.
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