Synthesis and Antitubercular,Antimicrobial, and Hemolytic Activity of Methyl D-Glucopyranuronate and Its Simplest Derivatives |
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| Authors: | M?G?Belenok O?V?Andreeva B?F?Garifullin A?S?Strobykina M?A?Kravchenko A?D?Voloshina Email author" target="_blank">V?E?KataevEmail author |
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| Institution: | 1.Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center,Russian Academy of Sciences,Kazan, Tatarstan,Russia;2.Ural Research Institute of Phthisiopulmonology,Ministry of Health Protection of the Russian Federation,Yekaterinburg,Russia |
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| Abstract: | Methyl glucuronate and some of its simplest derivatives have been synthesized, and their antitubercular, antimicrobial, and hemolytic activities have been studied. The simplest derivatives of glucuronic acid have been shown for the first time to exhibit a high antitubercular activity which is comparable with the activity of isoniazid. |
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