Ferric Perchlorate Catalyzed One‐pot Synthesis of 1,2,3,4‐Tetrahydro‐2‐pyrimidinones and ‐thiones: an Expedient Protocol for the Biginelli Reaction |
| |
Authors: | Majid Momahed HERAVI Farahnaz Kargar BEHBAHANI Hossien Abdi OSKOOIE |
| |
Affiliation: | Department of Chemistry, School of Sciences, Azzahra University, Vanak, Tehran, Iran |
| |
Abstract: | An efficient synthesis of 1,2,3,4‐tetrahydro‐2‐pyrimidinones and ‐thiones using ferric perchlorate as the catalyst from an aldehyde, ethyl acetoacetate, and urea or thiourea in acetonitrile was described. Compared to the classical Biginelli reaction conditions, this new method consistently has the advantage of full catalysis, good yields and short reaction time. |
| |
Keywords: | Biginelli reaction tetrahydropyrimidinone ferric perchlorate three component reaction |
|
| 点击此处可从《中国化学》浏览原始摘要信息 |
|
点击此处可从《中国化学》下载全文 |
|