Negishi cross-coupling of secondary alkylzinc halides with aryl/heteroaryl halides using Pd-PEPPSI-IPent |
| |
| Authors: | Çalimsiz Selçuk Organ Michael G |
| |
| Institution: | Department of Chemistry, York University 4700 Keele Street, Toronto, ON, M3J1P3, Canada. |
| |
| Abstract: | Pd-PEPPSI-IPent has proven to be an excellent catalyst for the Negishi cross-coupling reaction of secondary alkylzinc reagents with a wide variety of aryl/heteroaryl halides. Importantly, β-hydride elimination/migratory insertion of the organometallic leading to the production of isomeric coupling products has been significantly reduced using the highly-hindered Ipent ligand. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
