Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran ; Department of Chemistry, Facualty of Science, Gonbad Kavous University, P.O.Box 163, Gonbad, Iran
Abstract:
An efficient synthesis of methyl 4-hydroxy-6-oxo-1,6-dihydro-2-pyridine carboxylates is described.This involves three component reactions between primary alkyl amines,malonyl dichloride and methyl propiolates.