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Solvent-free one-pot synthesis of 2-pyridone derivatives |
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| Authors: | Zinatossadat Hossainia Faramarz Rostami-Charatib Rahimeh Hajinasiria Mohammad AKhalilzadeha a |
| Institution: | Department of Chemistry, Qaemshahr Branch, Islamic Azad University, ?Qaemshahr, Iran ; Department of Chemistry, Facualty of Science, Gonbad Kavous University, P.O.Box 163, Gonbad, Iran |
| Abstract: | An efficient synthesis of methyl 4-hydroxy-6-oxo-1,6-dihydro-2-pyridine carboxylates is described.This involves three component reactions between primary alkyl amines,malonyl dichloride and methyl propiolates. |
| Keywords: | One-pot reactions Multicomponent reactions Methyl propiolatc Green chemistry |
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