| 咖酚伪麻片中盐酸伪麻黄碱的含量 |
| |
| 引用本文： | 刘春光.咖酚伪麻片中盐酸伪麻黄碱的含量[J].光谱实验室,2011,28(4):2004-2007. |
| |
| 作者姓名： | 刘春光 |
| |
| 作者单位： | 内蒙古通辽制药股份有限公司 内蒙古通辽市中心大街196号028007 |
| |
| 摘 要： | 建立高效液相色谱法测定咖酚伪麻片中盐酸伪麻黄碱含量的方法。色谱柱为C18（150mm×4.6mm×5μm）,流动相为0.05mol/L磷酸二氢钠-甲醇（75∶25）,流速为1mL/min,检测波长为210nm。盐酸伪麻黄碱在0.2155—1.0776μg/g范围内线性良好,r=0.9999;盐酸伪麻黄碱的平均收率为100.92%,RSD值为0.41%（n=5）。此法操作简单,准确性好,可用于咖酚伪麻片中盐酸伪麻黄碱的含量测定。
|
| 关 键 词： | 咖酚伪麻片 盐酸伪麻黄碱 高效液相色谱法 |
Determination of Pseudoephedrine Hydrochloride in Paracetamol,Pseudoephedrine Hydrochloricle and Caffeine Tablets |
| |
| LIU Chun-Guang.Determination of Pseudoephedrine Hydrochloride in Paracetamol,Pseudoephedrine Hydrochloricle and Caffeine Tablets[J].Chinese Journal of Spectroscopy Laboratory,2011,28(4):2004-2007. |
| |
| Authors: | LIU Chun-Guang |
| |
| Institution: | LIU Chun-Guang(Inner Mongolia Tongliao Pharmaceutical Co.,LTD,Tongliao,Inner Mongolia 028007,P.R.China) |
| |
| Abstract: | The method for the determination of the content of the pseudoephedrine hydrochloride in the paracetamol,pseudoephedrine hydrochloricle and caffeine tablets was established by high performance liquid chromatography（HPLC）.The chromatograph column was C18（150mm×4.6mm×5μm）,and the mobile phase was 0.05mol / L sodium dihydrogen phosphate-methanol（75∶25） with flow rate of 1mL/min at detection wavelength of 210nm.There was a good linearity for pseudoephedrine hydrochloride in the range of 0.2155—1.0776μg/g with r=0.9999.The average recovery was 100.92% with RSD of 0.41%（n=5）.The method is simple,and has good accuracy,and can be applied to determination of pseudoephedrine hydrochloride in the paracetamol,pseudoephedrine hydrochloricle and caffeine tablets. |
| |
| Keywords: | Paracetamol Pseudoephedrine Hydrochloride and Caffeine Tablets Pseudoephedrine Hydrochloride HPLC |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
