Two three-dimensional Er(III) and In(III) metal-organic compounds: synthesis,crystal structures and antitumor activity in human glioma cells

Abstract

Two C₃-symmetric ligands, 4,4′,4″-1,3,5-benzenetriyltris(carbonylimino)]trisbenzoic acid (H₃BTA) and benzene-1,3,5-trisbenzoic acid (H₃BTB), were used to coordinate Er(III) and In(III). Reactions of the two C₃-symmetric ligands with Er(NO₃)₃·6H₂O and In(NO₃)₂·3H₂O under solvothermal conditions resulted in formation of two new three-dimensional porous coordination polymers, Er(BTA)(DMF)](DMF)₂(H₂O) (1) and In(H₂O)(BTB)](DMF)₂ (2). In addition, in vitro anticancer activities of 1 and 2 on three human glioma cells (SHG-44, SWO-38, and TJ905) were determined.