An iron(III) 18-metallacrown-6 complex: synthesis,crystal structure,and bioactivity |
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Abstract: | A macrocyclic hexanuclear iron(III) 18-metallacrown-6 complex, Fe6(C9H6BrN2O3)6(CH3OH)4(H2O)2]?·?7CH3OH?·?4H2O, has been prepared using a trianionic pentadentate ligand N-acetyl-5-bromosalicylhydrazidate, abshz3–, and characterized by X-ray diffraction. The crystal structure contains a neutral 18-membered metallacrown ring consisting of six Fe(III) and six abshz3– ligands. The 18-membered metallacrown ring is formed by combination of six structural moieties, Fe(III)–N–N]. Due to meridional coordination of ligand to Fe3+, the ligand enforces the stereochemistry of the Fe3+ ions as a propeller configuration with alternating Δ/Λ forms. Methanol and water are linked with Fe1, Fe1A, Fe,3 and Fe3A. The ratios of methanol to water are 0.76?:?0.24 for Fe1 and Fe1A, and 0.30?:?0.70 for Fe3 and Fe3A, which results in four component crystals of metallacrown rings with ratio of 0.168?:?0.072?:?0.532?:?0.228. Antibacterial screening data showed that the iron metallacrown has moderate antimicrobial activity against Bacillus subtilis. |
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Keywords: | Metallacrown Iron complex Crystal structure Antimicrobial activity |
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