Crystal structure,electrochemical, and antibacterial activity of the sodium complex formed by o-vanillin salicylhydrazone

The mononuclear sodium(I) complex [NaL(HL)] (1) [where HL is (OH)C₆H₄–CO–HN–N=CC₆H₃(OMe)(OH) synthesized by condensation of o-vanillin and salicyloylhydrazine] has been prepared and characterized by IR, elemental analysis, single crystal X-ray diffraction, and cyclic voltammetry. Single crystal X-ray diffraction analysis reveals that NaL(HL) is a neutral complex. Each six-coordinate Na(I) in the unit is linked through O bridges forming a ladder-like arrangement of the 1-D Na(I) double chain. The oxidation–reduction processes have been determined in CH₃CN by cyclic voltammetry. The complex displayed two quasi-reversible reduction couples and one oxidation response between +1.0 and ?0.6 V. The trend in the half wave potentials reflects the electronic nature of the hydrazone ligand. The antibacterial activity results show that the complex possesses strong inhibition activity against Staphyloccus aureus and Bacillus subtilis.