Synthesis,crystal structures,thermal properties,and DNA-binding studies of transition metal complexes with imidazole ligands |
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| Abstract: | A new series of complexes of transition metal (Cu, Zn, Ni) perchlorate with imidazole have been synthesized and characterized by elemental analysis, infrared (IR), UV-Vis spectroscopy, and single-crystal X-ray diffraction. Based on elemental and spectral data, the complexes are M(C3H4N2) x (ClO4)2 (M?=?Cu, Zn, x?=?4; M?=?Ni, x?=?6; C3H4N2?=?imidazole). The crystal structures of Cu(C3H4N2)4(ClO4)2 (1) and Zn(C3H4N2)4(ClO4)2 (2) show metals surrounded by four nitrogens of imidazole, while the nickel complex Ni(C3H4N2)6(ClO4)2 (3) has six nitrogens of imidazole. Intra- and inter-molecular hydrogen bonds exist between hydrogen of imidazole and oxygen of perchlorate. The thermal stabilities of 1, 2, and 3 at different heating rates (β?=?5°C?min?1, 10°C?min?1, and 15°C?min?1) show that all the complexes exhibit two thermal decomposition stages; the sequence of thermal stability is 2?>?1?>?3. 1, 2, 3, and imidazole display DNA binding ability, ascertained by UV-Vis titration. |
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| Keywords: | Transition metal Imidazole Crystal structure Thermal stability Interaction with CT-DNA |
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