| 宫内节育器铜管铜离子释放特性研究 |
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| 引用本文： | 金诚,孙江涛,由臣,王晓伟,谢祥,陈民芳.宫内节育器铜管铜离子释放特性研究[J].天津理工大学学报,2011,27(4):5-7. |
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| 作者姓名： | 金诚 孙江涛 由臣 王晓伟 谢祥 陈民芳 |
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| 作者单位： | 天津理工大学材料科学与工程学院,天津,300384 |
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| 基金项目： | 教育部大学生创新实验计划(091006003); 国家自然科学基金(51071108); 天津市自然科学基金重点项目(09JCZDJC18500) |
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| 摘 要： | 本文对临床应用载铜宫内节育器(CuIUD)铜管进行了模拟宫腔液浸泡实验,采用原子吸收光谱仪测试不同浸泡时间后模拟宫腔液中铜离子释放浓度,利用SEM和XRD观察、分析铜管表面形貌及物相组成,结果表明:经一个月浸泡,铬酸钝化膜与铜氧化物混合层使铜离子释放缓慢均匀;经两个月浸泡,混合层脱落基体暴露,腐蚀加剧,出现铜离子"暴释";经三个月浸泡,基体上生成了铜氧化层,使铜离子均匀稳定的释放.由此可推断,若在铜管表面预先制备一层氧化膜,可改变节育器植入子宫初期铜离子"暴释"现象.
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| 关 键 词： | 宫内节育器 铜离子 腐蚀 暴释 |
The study on IUDs release copperions |
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| JIN Cheng,SUN Jiang-tao,YOU Chen,WANG Xiao-wei,XIE Xiang,CHEN Ming-fang.The study on IUDs release copperions[J].Journal of Tianjin University of Technology,2011,27(4):5-7. |
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| Authors: | JIN Cheng SUN Jiang-tao YOU Chen WANG Xiao-wei XIE Xiang CHEN Ming-fang |
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| Institution: | JIN Cheng,SUN Jiang-tao,YOU Chen,WANG Xiao-wei,XIE Xiang,CHEN Ming-fang(School of Materials Science and Engineering,Tianjin University of Technology,Tianjin 300384,China) |
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| Abstract: | The clinical applications of copper intrauterine device(CuIUD) has been simulated through the uterine fluid immersion test.The concentrations of copper ions in simulated uterine fluid with different immersed time are investigated by using atomic absorption spectrometer.The morphology and the phase composition of the surface layer are characterized by scanning electron microscopy(SEM) and X-ray diffraction(XRD).The experimental results show: after a month's immersion,the copper ions release slowly due to the... |
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| Keywords: | CuIUD copper ions corrosion violent release |
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