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The synthesis of the potent anti-herpes virus agent, E-5(2-bromovinyl)-2′-deoxyuridine and related compounds
Authors:A.S. Jones  G. Verhelst  R.T. Walker
Affiliation:The Chemistry Department, Birmingham University, Birmingham B15 2TT, U.K.
Abstract:The synthesis of E-5(2-bromovinyl)-2′-deoxyuridine in good yield from deoxyuridine via an intermediate organopalladium derivative is described. The corresponding chloro and iodo compounds have also been made as have the corresponding bromo and iodo 2′-deoxycytidines.
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