The synthesis of the potent anti-herpes virus agent, -5(2-bromovinyl)-2′-deoxyuridine and related compounds |
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Authors: | A.S. Jones G. Verhelst R.T. Walker |
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Affiliation: | The Chemistry Department, Birmingham University, Birmingham B15 2TT, U.K. |
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Abstract: | The synthesis of -5(2-bromovinyl)-2′-deoxyuridine in good yield from deoxyuridine an intermediate organopalladium derivative is described. The corresponding chloro and iodo compounds have also been made as have the corresponding bromo and iodo 2′-deoxycytidines. |
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