Synthesis of thromboxane A2 analog dl-(9,11),(11,12)-dideoxa-(9,11),(11,12)-dimethylene thromboxane A2 |
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| Authors: | Shuichi Ohuchida Nobuyuki Hamanaka Masaki Hayashi |
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| Institution: | Research Institute, ONO Pharmaceutical Co., Ltd. 3-1-1 Sakurai, Shimamoto-cho, Mishima-gun, Osaka 618, Japan |
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| Abstract: | The thromboxane A2 analog, dl-(9,11),(11,12)-dideoxa-(9,11),(11,12)-dimethylene thromboxane A2 (TX A2) has been synthesized; the compound showed high agonist activities on platelet aggregation and the aorta contracting activities. |
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