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Facile synthesis of N-Cbz-α-dehydroamino acids and their dipeptide derivatives
Authors:Chung-gi Shin  Yasuchika Yonezawa  Kazuo Unoki  Juji Yoshimura
Affiliation:1. Laboratory of Chemistry for Natural Products, Tokyo Institute of Technology, Midori-ku, Yokohama 227, Japan
Abstract:N-Cbz-α-dehydroamino acis (DHA) were prepared by the condensation of α-keto acid with benzyl carbamate by one step and the subsequent coupling of the DHA with L-α-amino acid esters was carried out to give many kinds of dehydrodipeptides.
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