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A facile route to cyclopentenones by friedel-crafts acylation
Authors:Salih Hacini  Roselyne Pardo  Maurice Santelli
Affiliation:Centre de St-Jérome, Rue H. Poincaré, 13397-MARSEILLE Cedex 4 France
Abstract:Various cyclopentenones are obtained in fair to high yields when ethylenic acyl bromides are condensed with cyclohexene at low temperature. With less reactive reagents, condensation occurs at 0 °C, leading to β-chloro-ketones. A muscone precursor is obtained in two steps with excellent yields.
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