Synthesis of a protein biosynthesis inhibitor, 5′-tri-phosphoryladenylyl-(2′-5′)-adenosine |
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Authors: | Morio Ikehara Kazuyuki Oshie Eiko Ohtsuka |
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Affiliation: | Faculty of Pharmaceutical Sciences, Osaka University Suita, Osaka, Japan 565 |
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Abstract: | A protein biosynthesis inhibitor, 5′-triphosphoryladenylyl-(2′-5′)-adenylyl-(2′-5′)-adenosine was synthesized by polymerization of N6-benzoyl-3′-O-(o-nitrobenzyl)adenosine 5′-phosphate follwed by reaction with pyrophosphate using 1,1′-carbonyldiimidazole. |
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