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Synthesis of a protein biosynthesis inhibitor, 5′-tri-phosphoryladenylyl-(2′-5′)-adenosine
Authors:Morio Ikehara  Kazuyuki Oshie  Eiko Ohtsuka
Affiliation:Faculty of Pharmaceutical Sciences, Osaka University Suita, Osaka, Japan 565
Abstract:A protein biosynthesis inhibitor, 5′-triphosphoryladenylyl-(2′-5′)-adenylyl-(2′-5′)-adenosine was synthesized by polymerization of N6-benzoyl-3′-O-(o-nitrobenzyl)adenosine 5′-phosphate follwed by reaction with pyrophosphate using 1,1′-carbonyldiimidazole.
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