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Synthesis of 16-membered ring macrolide antibiotics I. Stereoselective construction of the ‘right wing” of the carbomycins and leucomycins from D-glucose
Authors:KC Nicolaou  MR Pavia  SP Seitz
Institution:Department of Chemistry, University of Pennsylvania Philadelphia, PA 19104 U.S.A.
Abstract:D-Glucose was converted to a backbone chain containing the appropriate functionalities and correct stereochemistry for the construction of the C1–C9 fragment of the 16-membered ring macrolide antibiotics carbomycin A and B and leucomycin A3.
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