Marine natural products: Cytotoxic spermidine derivatives from the soft coral sinularia brongersmai |
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| Authors: | Francis J. Schmitz K.H. Hollenbeak R.S. Prasad |
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| Affiliation: | Department of Chemistry, University of Oklahoma Norman, Oklahoma 73019 U.S.A. |
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| Abstract: | Two new cytotoxic spermidine derivatives isolated from the Pacific soft coral have been identified as CH3(CH28-C(CH3)=CH-CO-NH(CH2)3-N(CH3)- (CH2)4-N(CH3)2 and its dihydro analog by spectral methods combined with chemical conversions. Acid hydrolysis of the saturated amide followed by esterification yielded methyl 3-methyldodecanoate. |
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