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Fluorescence turn-on chemosensor for Hg~(2+) based on a rhodamine derivative and its application in bioimaging
Authors:LIU Chun    ZHOU ZhiGuo  GAO Yuan  YANG Hong  LI BaoGuo  LI FuYou & HUANG ChunHui School of Chemistry    Chemical Engineering  Inner Mongolia University  Hohhot   China
Affiliation:LIU Chun1,2,ZHOU ZhiGuo2,GAO Yuan2,YANG Hong2,LI BaoGuo1,LI FuYou2 & HUANG ChunHui2 1 School of Chemistry , Chemical Engineering,Inner Mongolia University,Hohhot 010021,China,2 Department of Chemistry,Fudan University,Shanghai 200433
Abstract:A fluorescence turn-on chemosensor based on rhodamine B derivative (FD10) has been developed as a highly sensitive chemosensor for Hg2+. A prominent fluorescence enhancement was measured in the presence of Hg2+, which was in agreement with the changes in the absorption spectrum. Furthermore, by means of laser scanning fluorescence microscopy experiments, it was demonstrated that FD10 was cell-permeable and could be used as a fluorescent probe for monitoring Hg2+ in living cells.
Keywords:chemosensor  fluorescence  rhodamine  bioimaging  
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