| 用于荧光免疫光纤生物传感器中信号分析的理论模型 |
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| 引用本文： | 王京生,冯莹,陈爽,魏立安,柳珑.用于荧光免疫光纤生物传感器中信号分析的理论模型[J].光子学报,2009,38(7):1647-1650. |
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| 作者姓名： | 王京生 冯莹 陈爽 魏立安 柳珑 |
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| 作者单位： | 国防科技大学,光电科学与工程学院,长沙,410073 |
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| 基金项目： | 国防科技大学基础研究项目 |
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| 摘 要： | 利用多层介质中偶极子辐射理论,得到了荧光免疫光纤生物传感器的初始荧光分布.在此基础上,利用几何光波导理论给出了荧光信号在光纤探针中的传输模型.通过定义光纤探针的耦合效率、传输效率、收集效率和有效收集效率等概念,实现了对基于倏逝波激发的荧光免疫光纤生物传感器系统中荧光信号的跟踪分析.并建立了理论模型,可用于该类传感器系统的优化设计.
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| 关 键 词： | 光纤生物传感器 荧光信号分析模型 偶极子辐射 几何光波导理论 效率 |
| 收稿时间： | 2008-03-21 |
| 修稿时间： | 2008-06-18 |
Theoretical Model Used for the Analysis of the Signal of Fluorimmunoassays Fiber-Optic Biosensor |
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| WANG Jing-sheng,FENG Ying,CHEN Shuang,WEI Li-an,LIU Long.Theoretical Model Used for the Analysis of the Signal of Fluorimmunoassays Fiber-Optic Biosensor[J].Acta Photonica Sinica,2009,38(7):1647-1650. |
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| Authors: | WANG Jing-sheng FENG Ying CHEN Shuang WEI Li-an LIU Long |
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| Institution: | College of Optolectronic Science and Engineering;National University of Defense Technology Changsha 410073;China |
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| Abstract: | Using the theory of radiation of dipoles placed within a multilayer system,the original distribution of fluorescence of flour-immunoassays fiber optic biosensor is presented.The transmission model of fluorescence signal is achieved by using the classical geometric optical waveguide theory.After introducing the Coupling Efficiency,the Transporting Efficiency,the Collecting Efficiency and the Effective Collecting Efficiency,the analysis of fluorescence signal of the fiber-optic biosensor based on evanescent w... |
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| Keywords: | Fiber optic biosensor Analysis model of fluorescence signal Radiation of dipoles Geometric optical waveguide theory Efficiency |
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