Disarming Clostridium difficile |
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| Authors: | Gersch Malte Sieber Stephan A |
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| Institution: | Department of Chemistry, Center for Integrated Protein Science Munich (CIPS(M)), Technische Universit?t München, Lichtenbergstr. 4, 85747 Garching, Germany. |
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| Abstract: | In this issue, Puriet al. (2010) present inhibitors that prevent the autocatalytic activation of the clostridial toxin TcdB in vivo. Their approach is likely to provide guidance for the development of novel drugs targeting virulence factors and thereby rendering bacterial pathogens innocuous. |
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