| SYNTHESIS AND BIOLOGICAL ACTIVITY OF A NEW FROG SKIN PEPTIDE, RANAMARGARIN |
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| 引用本文： | 陆一安,彭金林,朱应麒,吴时祥,唐易全,田盛海,邹冈. SYNTHESIS AND BIOLOGICAL ACTIVITY OF A NEW FROG SKIN PEPTIDE, RANAMARGARIN[J]. 中国科学B辑(英文版), 1990, 0(2) |
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| 作者姓名： | 陆一安 彭金林 朱应麒 吴时祥 唐易全 田盛海 邹冈 |
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| 作者单位： | Shanghai Centre of Biotechnology，Academia Sinica，Shanghai 200233，PRC，Shanghai Centre of Biotechnology，Academia Sinica，Shanghai 200233，PRC，Shanghai Centre of Biotechnology，Academia Sinica，Shanghai 200233，PRC，Shanghai Institute of Materia Medica，Academia Sinica，Shanghai 200031，PRC，Shanghai Institute of Materia Medica，Academia Sinica，Shanghai 200031，PRC，Shanghai Institute of Materia Medica，Academia Sinica，Shanghai 200031，PRC，Shanghai Institute of Materia Medica，Academia Sinica，Shanghai 200031，PRC |
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| 基金项目： | Project supported by the National Natural Science Foundation of China. |
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| 摘 要： | A new frog skin peptide, ranamargarin depicted as H-Asp-Asp-Ala-Ser-Asp-Arg-Ala-Lys-Lys-Phe-Tyr-Gly-Leu-Met-NH_(2′), was synthesized by the conventionalmethod. Comparisons of chemical and biological properties of both the synthetic and natural ranamargarins indicated that they were identical, so the chemical structure of ranamargarin was confirmed. Preliminary pharmacological study showed that ranamargarin was highly selective towards the SP-P subtype receptor.
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SYNTHESIS AND BIOLOGICAL ACTIVITY OF A NEW FROG SKIN PEPTIDE, RANAMARGARIN |
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| LU YI-AN PENG JIN-LIN ZHU YING-QI. SYNTHESIS AND BIOLOGICAL ACTIVITY OF A NEW FROG SKIN PEPTIDE, RANAMARGARIN[J]. Science in China(Chemistry), 1990, 0(2) |
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| Authors: | LU YI-AN PENG JIN-LIN ZHU YING-QI |
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| Abstract: | |
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| Keywords: | new frog skin tachykinin ranamargarin synthesis SP-P subtype receptor. |
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