4-Hydroxy-2-quinolones. 47. Synthesis and Diuretic Activity of (2H-1,2,4-Benzothiadiazine-1,1-dioxide-3-yl)methylamides of 1-R-4-Hydroxy-2-oxoquinoline-3-carboxylic Acids |
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| Authors: | S. G. Taran I. V. Ukrainets N. V. Likhanova O. V. Gorokhova P. A. Bezugly |
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| Affiliation: | (1) National Pharmaceutical Academy of the Ukraine, Kharkov, 310002 |
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| Abstract: | With the aim of investigating the relationship between chemical structure and biological activity we have synthesized and studied the effect of (2H-1,2,4-benzothiadiazine-1,1-dioxide-3-yl)methylamides of 1-R-4-hydroxy-2-oxoquinoline-3-carboxylic acids on kidney urinary output. |
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| Keywords: | benzothiadiazine diuretics carbostyril 4-hydroxy-2-quinolone |
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