Dynamic NMR study of cyclic derivatives of pyridoxine |
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| Authors: | I.Z. Rakhmatullin L.F. Galiullina M.R. Garipov A.D. Strel'nik Y.G. Shtyrlin V.V. Klochkov |
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| Affiliation: | Kazan (Volga Region) Federal University, , 420008 Kazan, Russian Federation |
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| Abstract: | A series of pyridoxine derivatives was investigated by 1H and 2D nuclear overhauser enhancement spectroscopy (NOESY) NMR. The free energies of activation for the pyridyl‐oxygen rotation of the 2,4‐dinitrophenyl ether of the seven‐membered acetals of pyridoxine were measured by dynamic NMR. A conformational exchange between the chair and twist forms of the seven‐membered acetal ring was confirmed by dynamic NMR and STO3G computations. Copyright © 2014 John Wiley & Sons, Ltd. |
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| Keywords: | dynamic 1H NMR energy barrier pyridoxine |
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