Group separation of organic nitrates on a new nitric acid ester NP-LC stationary phase |
| |
Authors: | J Kastler V Dubourg R Deisenhofer K Ballschmiter |
| |
Institution: | (1) Department of Analytical and Environmental Chemistry, University of Ulm, Albert-Einstein-Allee 11, 89081 Ulm, Germany;(2) Institut de Chimie et Physique Industrielles de Lyon, 31, Place Bellecourt, 69002 Lyon, France |
| |
Abstract: | Summary The synthesis of a nitric acid ester NP-LC stationary phase (organonitrate phase), by nitrating a commercial polyol phase
(Serva, Polyol Si 100, 5 μm) with mixed sulfuric-and nitric acid, is reported. The nitric acid ester bond is quite stable
towards hydrolysis. To examine its possible use as a stationary phase for the group separation of alkyl nitrates, several
bifunctional polar alkyl nitrates (di-nitrates, hydroxy-nitrates, keto-nitrates) have been synthesized. In order to simplify
their names a new abbreviating nomenclature for multifunctional organic nitrates is presented. With our new stationary phase
it is possible to separate mono-, di-, and hydroxy-nitrates as groups completely, a major advantage in sample preparation
in the chemistry of smog formation. However a co-elution of di- and keto-nitrates is observed. A distinction of the latter
two organonitrate groups is possible by gas chromatography-mass spectrometric detection (MSD). Apart from the fragment ion
NO2
+ (m/z=46 amu), which is nearly specific for alkyl nitrates, aliphatic di- and keto-nitrates show different characteristic
fragment ions. |
| |
Keywords: | Column liquid chromatography Nitric acid ester phase Alkyl nitrates Group separation |
本文献已被 SpringerLink 等数据库收录! |
|