吡啶二羧酸修饰的稀土嵌入碲钨酸盐的合成及电化学生物识别性质

在乙酸钠水溶液中, 采用微波加热一步自组装策略合成了一系列罕见的2,6-吡啶二羧酸修饰的稀土嵌入Keggin型碲钨酸盐(PTEA)₇H₃KRE₂(B-α-TeW₉O₃₃)₃W₃O₅(H₂O)₃(HDPA)]·22H₂ORE=Ce³⁺(1)， Pr³⁺(2)， Nd³⁺(3)， Sm³⁺(4); H₂DPA=2,6-吡啶二羧酸; PTEA=质子化的三乙醇胺]. 化合物1~4的聚阴离子由3个三缺位Keggin型 B-α-TeW₉O₃₃]^8-构筑块通过1个{RE₂W₃O₅(H₂O)₃(HDPA)}¹³⁺异金属簇连接而成. 该异金属簇中, 2,6-吡啶二羧酸作为四齿配体与2个稀土离子(RE1和RE2)配位形成平面三杂环结构, 且RE1和RE2所在平面与W2, W2A, W16形成的平面互相垂直. 此外, 化合物1可与羧基化多壁碳纳米管(CMWCNT)复合形成1-CMWCNT复合材料. 该复合材料可以作为电极材料构建电化学生物传感器, 用于检测特定的DNA序列.

Synthesis and Electrochemical Biosensing Properties of Pyridine Dicarboxylic Acid Decorated Rare-earth-incorporatedTellurotungstates

A family of rare 2，6-pyridinedicarboxylic acid decorated rare-earth（RE）-incorporated Keggin-type tellurotungstates（TTs）（PTEA）₇H₃K［RE₂（B-α-TeW₉O₃₃）₃W₃O₅（H₂O）₃（HDPA）］·22H₂O［RE=Ce³⁺（1）， Pr³⁺（2）， Nd³⁺（3）， Sm³⁺（4）； H₂DPA=2，6-pyridinedicarboxylic acid； PTEA=protonated triethanolamine］ were synthesized by the one-step self-assembly strategy in NaAc aqueous solution via microwave heating method. The polyanion of isomorphic compounds 1—4 consists of three trivacant Keggin ［B-α-TeW₉O₃₃］^8- building blocks linked by a ｛RE₂W₃O₅（H₂O）₃（HDPA）｝¹³⁺ heterometallic cluster. In this heterometallic cluster， HDPA as quadridentate ligand coordinates with two RE ions（RE1 and RE2） to form planar tri-heterocycle structure， which is perpendicular to the planar constructed by W2， W2A and W16 centers. Additionally， compound 1 can combinate with carboxylic multi-walled carbon nanotube（CMWCNT） to produce the 1-CMWCNT composite， which was then used as electrode material to establish electrochemical biosensor for detecting sequence-specific DNA.