|
|||||
|
|
An Absence of Non-specific Immune Response towards para-Sulphonato-calix[n]arenes |
|
| Authors: | Marie-Hélène Paclet Cécile F. Rousseau Campion Yannick Françoise Morel Anthony W. Coleman |
| Affiliation: | 1. GREPI, Laboratoire d’Enzymologie/DBPC, H?pital Albert Michallon – Centre Hospitalier Universitaire de Grenoble, BP 217, F38043, Grenoble Cedex 9, France 2. Laboratoire d’Assemblages Moléculaires d’Intérêt Biologique, Institut de Biologie et Chimie des Protéines, CNRS UMR 5086, 7 passage du Vercors, F69367, Lyon, France |
| Abstract: | The effects of para-Sulphonato-calix[4]arene, para-Sulphonato-calix[6]arene and para-Sulphonato-calix[8]arene on the activation of NADPH oxidase in neutrophils has been studied. All three molecules do not induce NADPH oxidase activation, and hence do not stimulate neutrophils. Measurement of cell viability demonstrates that these three water-soluble calix[n]arene derivatives are not cytotoxic. |
| Keywords: | calix[n]arenas neutrophils immune response cell mortality |
| 本文献已被 SpringerLink 等数据库收录！ | |