A Key Intermediate in Copper‐Mediated Arene Trifluoromethylation, [nBu4N][Cu(Ar)(CF3)3]: Synthesis,Characterization, and C(sp2)−CF3 Reductive Elimination |
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Authors: | Zehai Lu He Liu Shihan Liu Xuebing Leng Yu Lan Qilong Shen |
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Abstract: | The synthesis, characterization, and C(sp2)?CF3 reductive elimination of stable aryltris(trifluoromethyl)]cuprate(III) complexes nBu4N]Cu(Ar)(CF3)3] are described. Mechanistic investigations, including kinetic studies, studies of the effect of temperature, solvent, and the para substituent of the aryl group, as well as DFT calculations, suggest that the C(sp2)?CF3 reductive elimination proceeds through a concerted carbon–carbon bond‐forming pathway. |
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Keywords: | Fluor Kupfer Reduktive Eliminierung Trifluormethyl-Substituenten Ü bergangsmetalle |
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