Abstract: | In this study, natural‐based ionic liquid (IL) using caffeine (Caff), trietahnolamine (TEA) and ZnBr2, Caff‐TEA]+ZnBr3]?, which features high catalytic activity and environmentally‐friendly nature was synthesized with melting point of 76 °C by a facile method. The synthesized Caff‐TEA]+ZnBr3]? has high catalytic activity as both of catalyst and solvent in condensation reactions for the synthesis of benzylidenes, bis‐hydroxyenones and xanthenes. Synthesized IL was characterized by proton nuclear magnetic resonance (1HNMR), Fourier transform infrared spectroscopy (FT‐IR), X‐ray diffraction (XRD) and Energy‐dispersive X‐ray spectroscopy (EDX) analysis. Also synthesized heterocycles were characterized by FT‐IR, proton nuclear magnetic resonance (1HNMR) and carbon nuclear magnetic resonance (13CNMR). |