Carbonylation of C−N Bonds in Tertiary Amines Catalyzed by Low‐Valent Iron Catalysts |
| |
Authors: | Tawfiq Nasr Allah,Sol ne Savourey,Jean‐Claude Berthet,Emmanuel Nicolas,Thibault Cantat |
| |
Affiliation: | Tawfiq Nasr Allah,Solène Savourey,Jean‐Claude Berthet,Emmanuel Nicolas,Thibault Cantat |
| |
Abstract: | The first iron catalysts able to promote the formal insertion of CO into the C?N bond of amines are reported. Using low‐valent iron complexes, including K2[Fe(CO)4], amides are formed from aromatic and aliphatic amines, in the presence of an iodoalkane promoter. Inorganic Lewis acids, such as AlCl3 and Nd(OTf)3, have a positive influence on the catalytic activity of the iron salts, enabling the carbonylation at a low pressure of CO (6 to 8 bars). |
| |
Keywords: | Amide Carbonylierung Eisen Kohlenmonoxid Lewis-Sä uren |
|
|