高光谱成像技术在中医证候客观诊断中的应用

因高光谱成像技术具有灵敏度高、蕴含图谱信息丰富等特点,使其有望被作为突破口来解决中医证候诊断缺乏客观指标的困境。鉴于舌与证候之间存在复杂且模糊的映射关系,针对当前舌信息采集方式的局限性以及现有处理模式存在将混合信息体割裂提取以致重要内涵丢失的缺陷,提出了一种新思路:采用高光谱技术进行舌象采集并将舌体交叠混合的图谱信息作为一个整体进行分析,结合多种线性与非线性数据挖掘算法以黑箱模式关联证候,提取特异性光谱指标群。并将所提取的光谱指标群综合临床的生理、生化及中医症征指标,从多角度分析病因病机的机理,找到一种证候客观诊断的新模式。

Application of hyperspectral imaging technology to objective diagnosis of TCM syndrome

Hyperspectral imaging technology is expected as a breakthrough to resolve the lack of objective indicators on the diagnosis of TCM syndrome because of its high sensitivity and including abundant information of the images and spectra. In view of fuzzy and complicated mappings between tongue and syndrome, aiming at the defects of the acquisition methods of tongue information and its processing mode which extracts the features by fragmenting the integrative information, a new idea is proposed that the specific spectral indices pool be extracted after acquiring the hyperspectral data cube of tongue by hyperspectral imaging technology and associating it as a whole because of the overlapping mixing of these characteristic information with syndrome in black-box mode by means of intergration of various linear and nonlinear data mining algorithms. The mechanisms of etiological factor and pathogenesis are analyzed from all angles by synthesis of specific spectral indices pool, clinical physiological and biochemical indicators and TCM indicators. Then a new mode of objective diagnosis for syndromes can be found.