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A SONOCHEMICAL PROTOCOL FOR THE SYNTHESIS OF PERMODIFIED CYCLODEXTRINS[1]
Abstract:A series of O-peralkylated β- and γ-cyclodextrins, commonly used as stationary phases in high-resolution gas chromatography or as drug carriers, has been prepared both according to the usual methods and with sonocatalysis. The sonochemical protocol, using either a common cleaning bath or sonochemical apparatus, resulted in markedly improved yields, reaction times and reproducibility.
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