1,6‐C‐H and 1,5‐O‐Si Insertion Reactions of Alkylidenecarbene Derivatives of Monosaccharides* |
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Abstract: | A new protocol has been developed for the generation of alkylidenecarbene derivatives of monosaccharides based on the reaction of trimethylsilylazide and Bu2SnO with α‐cyanomesylates derived from uloses. When this method is applied to conveniently functionalized carbohydrate derivatives it provides novel heterocyclic ring systems by the rare 1,6‐C‐H or 1,5‐O‐Si insertion reactions. |
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Keywords: | Alkylidenecarbenes α‐Cyanomesylates Trimethylsilylazide Dibutyltin oxide Sugar templates 1 6‐C‐H Insertion 1 5‐O‐Si Insertion |
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