| Abstract: | The hydroxyethylated Achyranthes bidentata polysaccharides (Abps) were synthesized. The distribution of substituents in these derivatives was studied using HPLC and NMR analysis. The results show that the substituents are not homogeneously distributed along the Abps chain and the reactivity of the hydroxyl groups in the sugar units is OH‐4 ? OH‐3>OH‐6≈OH‐1. Bioassay showed that the derivative with a low degree of substitution (DS) was the best choice to inhibit the growth of Lewis pulmonary carcinoma. |
