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Intramolecular interaction in gibberic acid and its derivatives
Affiliation:1. Department of Pharmacognosy, College of Pharmacy, King Khalid University, P.O. Box 960, Abha 61421, Saudi Arabia;2. Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia;3. Department of Chemistry, Faculty of Science, Alexandria University, Ibrahimia, Alexandria, Egypt;4. Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt;5. Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura, Mansoura 35516, Egypt;6. Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, Abha 61441, Saudi Arabia;1. Department of Chemistry, Islamic University of Science and Technology, Awantipora Kashmir, 192122, India;2. Al-Muthanna University, College of Pharmacy, Muthanna State, Samawah 66001, Iraq;3. Department of Chemistry, Jain (Deemed-to-be) Univerity, Bengaluru, Karnataka, 560069, India;4. Department of Sciences, Vivekananda Global University Jaipur, Rajasthan, 303012, India;5. School of Basic and Applied Sciences, Shobhit University, Gangoh, Uttar Pradesh, 247341, India;6. Department of Health and Allied Sciences, Arka Jain University, Jamshedpur, Jharkhand, 831001, India;7. Department of Chemistry, Raghu Engineering College, Vishakapatnam, Andhra Pradesh, 531162, India;8. Department of Applied Sciences, Chandigarh Engineering College, Chandigarh Group of Colleges, Jhanjeri, Sahibzada Ajit Singh, Nagar, Punjab, 140307, India;9. Centre of Research Impact and Outcome, Chitkara University, Rajpura, 140417, Punjab India;10. Chitkara Centre for Research and Development, Chitkara University, Himachal Pradesh, 174103, India;11. School of Life and Applied sciences, Division of Research and Innovation, Uttaranchal University, Dehradun, Uttarakhand, India;12. Department of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia;13. Department of Chemistry, Howard University, Washington DC, 20059, USA;1. Shree Bhagubhai Mafatlal, Polytechnic College, Mumbai, India;2. Al-Muthanna University, College of Nursing, Mathanna State, Samawah 6600, Iraq;3. Engineering Department, Faculty of Engineering and Computer science, German University of Technology, Halban, Oman;4. Department of Research Institute of Preventive Medicine named Acedemician E.Dalenov, Astana Medical University, Astana 010000, Kazakhstan;5. Department of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia;6. Department of Chemistry, Howard University, Washington DC, 20059, USA;7. Department of Chemistry, Islamic University of Science and Technology, Awantipora Kashmir, 192122, India
Abstract:Spectroscopic investigation (u.v., i.r. and NMR) of gibberic acid, epigibberic acid, allogibberic acid and epiallogibberic acid suggests a weak intramolecular interaction of the aromatic ring with the terminal methylene group in the case of epiallogibberic acid, and with the terminal carbonyl group in the case of epigibberic acid.
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