A convenient new procedure for converting primary amides into nitriles |
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Authors: | Kuo Chun-Wei Zhu Jia-Liang Wu Jen-Dar Chu Cheng-Ming Yao Ching-Fa Shia Kak-Shan |
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Affiliation: | Division of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, 350, Taiwan, R.O.C. |
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Abstract: | An operationally simple and high-yielding procedure has been developed for the conversion of primary amides to the corresponding nitriles, using ethyl dichlorophosphate/DBU as the mild dehydrating agent. |
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