Direct C—H Bond Activation of Benzoxazole and Benzothiazole with Aryl Bromides Catalyzed by Palladium(II)‐N‐heterocyclic Carbene Complexes |
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Authors: | Murat Kalo?lu Nazan Kalo?lur ?smail Özdemir |
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Institution: | 1. Department of Chemistry, Faculty of Science and Arts, ?nönü University, 44280 Malatya, Turkey;2. Catalysis Research and Application Center, ?nönü University, 44280 Malatya, TurkeyE‐mail:
(?.Ö.);3. (M.K.);4. (N.K.);5. Department of Chemistry, Faculty of Science and Arts, ?nönü University, 44280 Malatya, TurkeyE‐mail:
(?.Ö.) |
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Abstract: | Herein, we report that a series of novel palladium(II)‐NHC complexes (NHC=N‐heterocyclic carbene) were synthesized. The structures of all novel complexes were characterized by 1H NMR, 13C NMR, FT‐IR spectroscopy and elemental analysis techniques. These palladium(II)‐NHC complexes were tested as efficient catalysts in the direct C—H bond activation of benzoxazole and benzothiazole with aryl bromides in the presence of 1 mol% catalyst loading at 150 °C for 4 h. Under the given conditions, various aryl bromides were successfully applied as the arylating reagents to achieve the 2‐arylbenzoxazoles and 2‐arylbenzothiazoles in acceptable to high yields. |
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Keywords: | benzimidazolium bromide benzoazoles direct C— H bond activation
N‐heterocyclic carbene palladium |
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