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Metal-free one-pot oxidative amidation of aldoses with functionalized amines
Authors:Colombeau Ludovic  Traoré Ténin  Compain Philippe  Martin Olivier R
Institution:Institut de Chimie Organique et Analytique, Université d'Orléans, CNRS UMR 6005, BP 6759, 45067 Orléans, France.
Abstract:Metal-free one-pot oxidative amidation of aldoses with functionalized amines using iodine provides a rapid access to functionalized aldonamides. The main advantage of this approach relies on the fact that aldehyde oxidation and C-N bond formation are performed in a single synthetic operation.
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