Metal-free one-pot oxidative amidation of aldoses with functionalized amines |
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Authors: | Colombeau Ludovic Traoré Ténin Compain Philippe Martin Olivier R |
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Institution: | Institut de Chimie Organique et Analytique, Université d'Orléans, CNRS UMR 6005, BP 6759, 45067 Orléans, France. |
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Abstract: | Metal-free one-pot oxidative amidation of aldoses with functionalized amines using iodine provides a rapid access to functionalized aldonamides. The main advantage of this approach relies on the fact that aldehyde oxidation and C-N bond formation are performed in a single synthetic operation. |
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