PHOTO-OXIDATION OF N'-FORMYLKYNURENINE AND TRYPTOPHAN PEPTIDES BY SUNLIGHT OR SIMULATED SUNLIGHT |
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| Authors: | Antoinette Pirie K. J. Dilley |
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| Affiliation: | Nuffield Laboratory of Ophthalmology, University of Oxford, Walton Street, Oxford OX2 6AW, England |
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| Abstract: | Abstract— N'-Formylkynurenine, a photochemical breakdown product of tryptophan in proteins, was exposed to sunlight or simulated sunlight at neutral pH. N-Formylanthranilic acid and 4-hydroxyquinoline were identified in the reaction products. Neither has been previously described as a photo-oxidation product of tryptophan-containing compounds. They were not found after photo-oxidation of glycyltryptophan or tryptophylglycine, although the indole ring was broken in both compounds. |
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