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Enantioselective synthesis of (-)-paeonilide
Authors:Harrar Klaus  Reiser Oliver
Affiliation:Institut für Organische Chemie, Universit?t Regensburg, Universit?tsstr. 31, 93053 Regensburg, Germany.
Abstract:The first enantioselective synthesis of (-)-paeonilide is reported. Starting from inexpensive furan-3-carboxylic acid the targeted monoterpene was obtained in 12 steps via an asymmetric cyclopropanation-lactonization cascade and a stereoselective side chain insertion at an acetal-like position.
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