Enantioselective synthesis of (-)-paeonilide |
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Authors: | Harrar Klaus Reiser Oliver |
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Affiliation: | Institut für Organische Chemie, Universit?t Regensburg, Universit?tsstr. 31, 93053 Regensburg, Germany. |
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Abstract: | The first enantioselective synthesis of (-)-paeonilide is reported. Starting from inexpensive furan-3-carboxylic acid the targeted monoterpene was obtained in 12 steps via an asymmetric cyclopropanation-lactonization cascade and a stereoselective side chain insertion at an acetal-like position. |
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