A convenient 1,3-dipolar cycloaddition approach to pyridylpyrroles |
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Authors: | Justin M. LopchukGordon W. Gribble |
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Affiliation: | Department of Chemistry, Dartmouth College, Hanover, NH 03755, USA |
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Abstract: | A variety of 2-, 3-, and 4-pyridylpyrroles were synthesized in good to excellent yields via the 1,3-dipolar cycloaddition of symmetrical and unsymmetrical münchnones and nitroalkenes. The unsymmetrical münchnones show moderate to excellent regioselectivity. |
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Keywords: | Mü nchnone 1,3-Dipolar cycloaddition Regioselectivity Nitroalkene Henry reaction |
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