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A convenient 1,3-dipolar cycloaddition approach to pyridylpyrroles
Authors:Justin M. LopchukGordon W. Gribble
Affiliation:Department of Chemistry, Dartmouth College, Hanover, NH 03755, USA
Abstract:A variety of 2-, 3-, and 4-pyridylpyrroles were synthesized in good to excellent yields via the 1,3-dipolar cycloaddition of symmetrical and unsymmetrical münchnones and nitroalkenes. The unsymmetrical münchnones show moderate to excellent regioselectivity.
Keywords:  nchnone   1,3-Dipolar cycloaddition   Regioselectivity   Nitroalkene   Henry reaction
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