Conformational properties and dynamics of protein-like chains confined in an infinite cylinder |
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Authors: | Weiqi Yi |
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Institution: | Department of Physics, Wenzhou Normal College, Wenzhou 325027, PR China |
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Abstract: | In this paper the conformational properties and dynamics of protein-like lattice chains confined in an infinite cylinder are investigated by using Monte Carlo simulation method and the hybrid (3 1 0) lattice model. When the diameter of infinite cylinder D is greater than 0.5-0.7RF, the shape of protein-like chains remains unchanged, here Flory radius RF is RF = 3.0N0.6. When D < 0.5RF, the confinement of the cylinder help to form the helices, however, it hinders to form the coils, and the shape of protein-like chains changes from sphere-like structure to rod-like one. Different confinements affect distinctly to form the secondary structure of proteins. There exist a different dynamics behavior between protein-like chains confined in an infinite cylinder and general protein-like chains without confinement. These investigations may provide some insights into the influence of crowding condition to the conformation properties and dynamics of proteins. |
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Keywords: | Confinement of cylinder Protein-like chain Conformation Dynamics |
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