| SmI_2-Mediated Addition Reaction of α-Halomethylsulfones to Carbonyl Compounds.A Convenient Synthesis of β-Hydroxysulfones |
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| 引用本文： | 黄宪,段德慧,金红卫.SmI_2-Mediated Addition Reaction of α-Halomethylsulfones to Carbonyl Compounds.A Convenient Synthesis of β-Hydroxysulfones[J].中国化学,2003(7). |
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| 作者姓名： | 黄宪 段德慧 金红卫 |
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| 作者单位： | Department of Chemistry，Zhejiang University(Xixi Campus)，Hangzhou，Zhejiang 310028，China，Department of Chemistry，Zhejiang University(Xixi Campus)，Hangzhou，Zhejiang 310028，China，Department of Chemistry，Zhejiang University(Xixi Campus)，Hangzhou，Zhejiang 310028，China |
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| 基金项目： | Project supported by the National Natural Science Foundation of China(No.20272050). |
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| 摘 要： | Due to the chemoselective dehalogenation by SmI_2, the additionof α-halomethylsulfones to carbonyl compounds afforded β-hy-droxysulfones. Those reactions with α-bromomethylsulfonesgave the products in moderate to good yields. The SmI_2-mediat-ed addition of gem-dihalomethylsulfones to ketones also afford-ed α-halo-β-hydroxysulfones in moderate yields.
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| 关 键 词： | SmI2-mediated addition synthesis β-hydroxysul-fones α-halo-β-hydroxysulfones |
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